Article
Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families.
World journal of gastroenterology - 7 Jul 2006
Wang Xu-Lin, Yuan Ying, Zhang Su-Zhan, Cai Shan-Rong, Huang Yan-Qin, Jiang Qiang, Zheng Shu
Abstract excerpt
AIM: To analyze the clinical characteristics of Chinese hereditary nonpolyposis colorectal cancer (HNPCC) families and to screen the germline mutations of human mismatch repair genes hMLH1 and hMSH2 in the probands. METHODS: Thirty-one independent Chinese HNPCC families were collected in Zhejiang Province. All of them met Chinese HNPCC criteria. Clinical data about patient gender, site of colorectal cancer, age...
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