Article
Association between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes in Chinese male nuclear families.
Acta pharmacologica Sinica - 1 Dec 2009
Gu Jie-mei, Xiao Wen-jin, He Jin-wei, Zhang Hao, Hu Wei-wei, Hu Yun-qiu, Li Miao, Liu Yu-juan, Fu Wen-zhen, Yu Jin-bo, Gao Gao, Yue Hua, Ke Yao-hua, Zhang Zhen-lin
Abstract excerpt
AIM: The goal of this study was to determine whether polymorphisms in the vitamin D receptor (VDR) and estrogen receptor alpha (ESR1) genes are associated with variations of peak bone mineral density (BMD) and obesity phenotypes in young Chinese men. METHODS: A total of 1215 subjects from 400 Chinese nuclear families were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
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