Article
Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral density and body composition in Chinese male nuclear families.
Journal of bone and mineral metabolism - 1 Jul 2017
Zhao Fei, Gao Li-Hong, Li Shan-Shan, Wei Zhan-Ying, Fu Wen-Zhen, He Jin-Wei, Liu Yu-Juan, Hu Yun-Qiu, Dong Jing, Zhang Zhen-Lin
Abstract excerpt
The methyltransferase-like 21C gene (METTL21C), which is mainly expressed in muscle, can promote the differentiation of myoblasts to myotubes and reduce glucocorticoid-induced apoptosis of osteocytes. The purpose of this study was to explore the association between single nucleotide polymorphisms of METTL21C and peak bone mineral density (BMD), body mass index, total fat mass (TFM), and total lean mass (TLM) in...
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