Article
A Polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study.
Calcified tissue international - 1 Feb 2012
Cusano Natalie E, Kiel Douglas P, Demissie Serkalem, Karasik David, Adrienne Cupples L, Corella Dolores, Gao Qiong, Richardson Kris, Yiannakouris Nikos, Ordovas Jose M
Abstract excerpt
There is increasing interest in identifying new pathways and candidate genes that confer susceptibility to osteoporosis. There is evidence that adipogenesis and osteogenesis may be related, including a common bone marrow progenitor cell for both adipocytes and osteoblasts. Perilipin 1 (PLIN1) and Perilipin 4 (PLIN4) are members of the PATS family of genes and are involved in lipolysis of intracellular lipid...
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