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Article

Structural studies of the catalytic core of the primate foamy virus (PFV-1) integrase.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Aug 2010

Réty Stéphane, Reaeábková Lenka, Dubanchet Barbara, Silhán Jan, Legrand Pierre, Lewit-Bentley Anita

Abstract excerpt

Retroviral integrases are vital enzymes in the viral life cycle and thus are important targets for antiretroviral drugs. The structure of the catalytic core domain of the integrase from human foamy virus, which is related to HIV-1, has been solved. The structure of the protein is presented in two different crystal forms, each containing several molecules in the asymmetric unit, with and without the essential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20693659
DOI: 10.1107/S1744309110022852
PMCID: PMC2917282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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