Article

Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses

2024-02-09

Abstract excerpt

Foamy viruses (FVs) constitute a subfamily of retroviruses. Their envelope glycoprotein (Env) drives the merger of viral and cellular membranes during entry into cells. The only available structures of retroviral Envs are those from human and simian immunodeficiency viruses from the subfamily of orthoretroviruses, which are only distantly related to the FVs. We report here the cryo-EM structures of the FV Env ecto...

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Literature Corpus work: 8a539769-bb8c-55b5-a6bb-793ca54e96c5
DOI: 10.1101/2024.02.09.579661

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