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Article

Deep sequencing analysis of mutations resulting from the incorporation of dNTP analogs.

Nucleic acids research - 1 Dec 2010

Petrie Katherine L, Joyce Gerald F

Abstract excerpt

Next-generation DNA sequencing technology was used to score >100,000 mutations resulting from exposure of a nucleic acid template to a mutagenic dNTP analog during a single pass of a DNA polymerase. An RNA template of known secondary structure was reverse transcribed in the presence of 8-oxo-dGTP...

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Identifiers

PMID: 20693528
DOI: 10.1093/nar/gkq685
PMCID: PMC3001061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20693528-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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