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Article

Evaluation of chemical mutagenicity using next generation sequencing: A review.

Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews - 3 Jul 2017

Du Hua, Pan Bohu, Chen Tao

Abstract excerpt

Mutations are heritable changes in the nucleotide sequence of DNA that can lead to many adverse effects. Genotoxicity assays have been used to identify chemical mutagenicity. Recently, next generation sequencing (NGS) has been used for this purpose. In this review, we present the progress in NGS application for assessing mutagenicity of chemicals, including the methods used for detecting the induced mutations,...

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PMID: 28506110
DOI: 10.1080/10590501.2017.1328831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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