Article

Rad51 and Mitotic Function of Mus81 are Essential for Recovery from Low-Dose of Camptothecin in the Absence of the Wrn Exonuclease

2018-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Stabilisation of the stalled replication fork is crucial to prevent excessive fork reversal or degradation, which can undermine genome integrity. The WRN protein is a human RecQ helicase that participates in the processing and recovery of perturbed replication forks. WRN is unique among the other human RecQ family members to possess exonuclease activity. However, the biological role of the WRN e...

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Literature Corpus work: 6d5ea74f-b610-5d77-a0c1-c11c0f969cb6
DOI: 10.1101/399881

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