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Article

Genetic variation within the beta1-adrenergic receptor gene results in haplotype-specific expression phenotypes.

Journal of cardiovascular pharmacology - 1 Jan 2008

Small Kersten M, Mialet-Perez Jeanne, Liggett Stephen B

Abstract excerpt

Cardiac beta1-adrenergic receptor (beta1AR) responsiveness in heart failure exhibits interindividual variation that may be attributable to polymorphisms of the intronless beta1AR gene. We sought to ascertain the polymorphisms of the full-length gene and the specific combinations of polymorphisms (haplotypes) in two reference populations. Using whole-gene transfections, we established the impact of beta1AR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18209576
DOI: 10.1097/FJC.0b013e31815a958f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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