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High frequency of X4/DM-tropic viruses in PBMC samples from patients with primary HIV-1 subtype-B infection in 1996-2007: the French ANRS CO06 PRIMO Cohort Study

2 May 2009

Abstract excerpt

OBJECTIVES: To estimate the frequency of viruses with X4 or dual-X4/DM tropism from peripheral blood mononuclear cells (PBMCs) of 390 human immunodeficiency virus type 1 (HIV-1) subtype-B patients diagnosed at the time of primary HIV-1 infection (PHI) between 1996 and 2007 and enrolled in the PRIMO Cohort. METHODS: V3 loop sequences were amplified from HIV-1-DNA and analysed with a combination of five genotypic...

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PMID: 19411680
DOI: 10.1093/jac/dkp151

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