Article
Influence of CD40 rs1883832 polymorphism in susceptibility to and clinical manifestations of biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 Oct 2010
Rodríguez-Rodríguez Luis, Castañeda Santos, Vázquez-Rodríguez Tomás R, Morado Inmaculada C, Marí-Alfonso Beatriz, Gómez-Vaquero Carmen, Miranda-Filloy José A, Narvaez Javier, Ortego-Centeno Norberto, Blanco Ricardo, Fernández-Gutiérrez Benjamín, Martín Javier, González-Gay Miguel A
Abstract excerpt
OBJECTIVE: To assess the potential association between CD40 rs1883832 polymorphism and biopsy-proven giant cell arteritis (GCA). We also studied the influence of the polymorphism on phenotypic expression of this vasculitis, in particular the development of visual ischemic manifestations. METHODS: Three hundred five Spanish patients with biopsy-proven GCA and 788 matched controls were assessed. DNA from patients...
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