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C-reactive protein gene polymorphisms influence susceptibility and outcomes of biopsy-proven giant cell arteritis in Italian patients.

Clinical and experimental rheumatology - 1 Apr 2024

Boiardi Luigi, Farnetti Enrico, Macchioni Pierluigi, Nicoli Davide, Croci Stefania, Muratore Francesco, Marvisi Chiara, Ricordi Caterina, Catanoso Mariagrazia, Galli Elena, Salvarani Carlo

Abstract excerpt

OBJECTIVES: To investigate potential associations between the two functional C-reactive protein (CRP) gene polymorphisms at position 3872C>T (rs1205) and 4741G>C (rs3093068) and susceptibility, clinical expression, laboratory and pathological findings, and outcomes of giant cell arteritis (GCA) in a Nothern Italian population. METHODS: One hundred and seventy Italian patients with biopsy-proven GCA resident in...

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PMID: 37534674
DOI: 10.55563/clinexprheumatol/z40y02

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