Article
Role of the CCR5/Δ32CCR5 polymorphism in biopsy-proven giant cell arteritis.
Human immunology - 1 May 2011
Carmona F David, Rodríguez-Rodríguez Luis, Castañeda Santos, Miranda-Filloy José A, Morado Inmaculada C, Narváez Javier, Marí-Alfonso Beatriz, Unzurrunzaga Ainhoa, Ríos-Fernández Raquel, Blanco Ricardo, de Miguel Eugenio, Martín Javier, González-Gay Miguel A
Abstract excerpt
To further explore the potential role of chemokines in giant cell arteritis (GCA), we have studied whether the CCR5/Δ32CCR5 polymorphism is implicated in the susceptibility to the disease and its specific features. A total of 352 Spanish patients with biopsy-proven GCA and 479 matched controls were assessed. DNA was obtained from peripheral blood. Samples were genotyped by PCR with specific primers spanning the...
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