Article
Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population.
Heart and vessels - 1 Sept 2010
Zhang Kai, Wang Yuan-yuan, Liu Qi-ji, Wang Hui, Liu Fang-fang, Ma Zhi-yong, Gong Yao-qin, Li Li
Abstract excerpt
Arachidonate 12/15-lipoxygenase (12/15-LOX) has been implicated in the pathogenesis of atherosclerosis, but with contradicting results. The aim of this study was to investigate the association of two polymorphisms in ALOX15 and the risk of coronary artery disease (CAD) in a Chinese Han population. A total of 519 unrelated CAD patients and 608 unrelated control subjects of the Chinese Han population were recruited...
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