Article
Association of polymorphisms in the ALOX15B gene with coronary artery disease.
Clinical biochemistry - 1 Apr 2014
Wuest Sophia J A, Horn Thomas, Marti-Jaun Jacqueline, Kühn Hartmut, Hersberger Martin
Abstract excerpt
BACKGROUND: Atherosclerosis is a multifactorial disease and the underlying cause of coronary artery disease (CAD), myocardial infarction and stroke. Two main features are involved in the progression of atherosclerosis, lipid retention and inflammation. 12/15-lipoxygenases are involved in inflammation and have been implicated in atherosclerosis. Genetic association studies of the 15-lipoxygenase 1 (ALOX15) in...
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