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Article

Association of ALOX5AP haplotypes with susceptibility to coronary artery disease in a Chinese Han population.

European journal of internal medicine - 1 Jul 2012

Li Yi, Li Zhidong, Zhang Xiaolin, Yan Chenghui, Kang Jian, Liang Zhenyang, Liu Shaowei, Feng Xueyao, Han Yaling

Abstract excerpt

BACKGROUND: The 5-lipoxygenase activating protein (FLAP), encoded by the activating 5-lipoxygenase (ALOX5AP) gene, is a crucial mediator of the biosynthesis of leukotrienes, which have been implicated in atherosclerosis. This study investigates whether ALOX5AP polymorphisms are associated with coronary artery disease (CAD) in a Chinese Han population. METHODS: The promoter, exons, splice site region and...

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Source

Identifiers

PMID: 22726381
DOI: 10.1016/j.ejim.2012.02.010

Genes

CAD
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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