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Article

Determination of hypersensitivity to genotoxic agents among Escherichia coli single gene knockout mutants.

DNA repair - 4 Sept 2010

Becket Elinne, Chen Frank, Tamae Cindy, Miller Jeffrey H

Abstract excerpt

We have tested the KEIO collection of 3985 different viable single gene knockouts in Escherichia coli to identify genes whose loss increases sensitivity to one or more of six different chemotherapeutic agents and mutagens: Bleomycin (BLM), Cisplatin (CPT), ICR-191 (ICR), 5-azacytidine (5AZ), Zebularine (ZEB), and 5-bromo-2'-deoxyuridine (5BdU). We discovered a set of 156 strains that display a significant...

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Identifiers

PMID: 20674514
DOI: 10.1016/j.dnarep.2010.06.008
PMCID: PMC2929269

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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