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Genome-Wide Screens Identify Genes Responsible for Intrinsic Boric Acid Resistance in Escherichia coli.

Biological trace element research - 1 Dec 2024

Çöl Bekir, Kürkçü Merve Sezer, Di Bek Esra

Abstract excerpt

Boric acid (BA) has antimicrobial properties and is used to combat bacterial infections, including Enterobacteria. However, the molecular mechanisms and cellular responses to BA are still unknown. This genomics study aims to provide new information on the genes and molecular mechanisms related to the antimicrobial effect of BA in Escherichia coli. The Keio collection of E. coli was used to screen 3985 single-gene...

Topics

Boric Acids
Escherichia coli
Drug Resistance, Bacterial
Genome, Bacterial
Microbial Sensitivity Tests
Anti-Bacterial Agents
Mutation
Escherichia coli Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38466471
DOI: 10.1007/s12011-024-04129-0
PMCID: PMC11502571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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