Article

Tazobactam selects for multidrug resistance

2023-08-15

Abstract excerpt

Piperacillin-Tazobactam is a β-lactam/β-lactamase inhibitor combination which is amongst the most prescribed antimicrobials in hospital medicine. Piperacillin is inactivated by commonly carried resistance enzymes, but tazobactam inhibits these allowing successful treatment. The effect of piperacillin on Gram-negative bacteria has been widely studied, but less attention has been paid to the effects of tazobactam. W...

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Literature Corpus work: 41744e12-d983-5d1e-98fb-413b510375af
DOI: 10.1101/2023.08.15.553388

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