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Article

LRRK2 Gly2385Arg polymorphism, cigarette smoking, and risk of sporadic Parkinson's disease: a case-control study in Japan.

Journal of the neurological sciences - 15 Oct 2010

Miyake Yoshihiro, Tsuboi Yoshio, Koyanagi Midori, Fujimoto Takahiro, Shirasawa Senji, Kiyohara Chikako, Tanaka Keiko, Fukushima Wakaba, Sasaki Satoshi, Yamada Tatsuo, Oeda Tomoko, Miki Takami, Kawamura Nobutoshi, Sakae Nobutaka, Fukuyama Hidenao, Hirota Yoshio, Nagai Masaki

Abstract excerpt

Previous case-control studies in Japanese and ethnic Chinese populations reported that the LRRK2 Gly2385Arg variant is a risk factor for Parkinson's disease (PD). We aimed to validate the previous findings and investigate whether cigarette smoking influences the relationship between the Gly2385Arg variant and PD. Included were 229 cases within 6years of onset of sporadic PD. Controls were 358 inpatients and...

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Identifiers

PMID: 20673920
DOI: 10.1016/j.jns.2010.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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