Article
Alleles of the IL12B 3'UTR associate with late onset of type 1 diabetes.
Human immunology - 1 Dec 2004
Windsor Lydia, Morahan Grant, Huang Dexing, McCann Vincent, Jones Timothy, James Ian, Christiansen Frank T, Price Patricia
Abstract excerpt
Carriage of a polymorphism in the 3'untranslated region of the IL12B gene encoding IL-12p40 was investigated in subjects with type 1 diabetes mellitus stratified by age at diagnosis (n = 648) and compared with a population-based control cohort (n = 246) residing in Western Australia. DNA samples were genotyped by polymerase chain reaction-restriction fragment length polymorphism or pyrosequencing. The C allele...
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