Article
Differential expression of genes in the calcium-signaling pathway underlies lesion development in the LDb mouse model of atherosclerosis.
Atherosclerosis - 1 Nov 2010
Mak Solida, Sun Hua, Acevedo Frances, Shimmin Lawrence C, Zhao Lei, Teng Ba-Bie, Hixson James E
Abstract excerpt
OBJECTIVE: Atherosclerosis is influenced by the interaction of environmental and genetic susceptibility risk factors. We used global microarray expression profiling to investigate differentially regulated genes in aorta during development of atherosclerosis in a susceptible genetically modified mouse model in response to the interaction between risk factors including hyperlipidemic genotype, shear stress, diet,...
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