Article
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease
4 May 2005
Abstract excerpt
The propensity for developing atherosclerosis is dependent on underlying genetic risk and varies as a function of age and exposure to environmental risk factors. Employing three mouse models with different disease susceptibility, two diets, and a longitudinal experimental design, it was possible to manipulate each of these factors to focus analysis on genes most likely to have a specific disease-related function....
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