Article
Microarray analysis of gene expression in mouse aorta reveals role of the calcium signaling pathway in control of atherosclerosis susceptibility.
American journal of physiology. Heart and circulatory physiology - 1 May 2009
Yuan Zuobiao, Miyoshi Toru, Bao Yongde, Sheehan Jason P, Matsumoto Alan H, Shi Weibin
Abstract excerpt
Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit a marked difference in atherosclerotic lesion formation when deficient in apolipoprotein E (apoE(-/-)), and the arterial wall has been identified as a source of the difference in atherosclerosis susceptibility. In the present study, differences in gene expression in aortic walls of the two strains were analyzed by microarrays. Total RNA was extracted...
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