Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A combination of functional polymorphisms in the CASP8, MMP1, IL10 and SEPS1 genes affects risk of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Feb 2011

Hart Kent, Landvik Nina E, Lind Helge, Skaug Vidar, Haugen Aage, Zienolddiny Shanbeh

Abstract excerpt

Exposure to tobacco smoke as well as environmental and occupational factors is the major cause of lung cancer. Non-small cell lung cancer (NSCLC) is the major histological type. Genes in pathways affecting inflammation, cellular stress and apoptosis are important, and the extent of inflammation in the lung could be affected by polymorphisms modifying these responses. In the present study we have investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Caspase 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-10

Share to Interleukin-1beta

Share to Lung Neoplasms

Share to Matrix Metalloproteinase 1

Share to Selenoproteins

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 20471133
DOI: 10.1016/j.lungcan.2010.04.016

Genes

CASP8
MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A combination of functional polymorphisms in the CASP8, MMP1, IL10 and SEPS1 genes affects risk of non-small cell lung cancer.PMID 20471133Read ↗

A literature-based systematic HuGE review and meta-analysis show that CASP gene family polymorphisms are associated with risk of lung cancer.Semantic proximity Read ↗

Polymorphisms in the caspase genes and the risk of lung cancer.Semantic proximity Read ↗

Polymorphisms in the caspase-8 gene and the risk of lung cancer.Semantic proximity Read ↗

Polymorphisms in the CASPASE genes and survival in patients with early-stage non-small-cell lung cancer.Semantic proximity Read ↗

TNF-alpha, TNF-beta, IL-6, and IL-10 polymorphisms in patients with lung cancer.Semantic proximity Read ↗

Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer.Semantic proximity Read ↗

Genetic polymorphisms of IL-10, IL-18 and IL12B are associated with risk of non-small cell lung cancer in a Chinese Han population.Semantic proximity Read ↗

Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure.Semantic proximity Read ↗

In silico analysis of DEL-1 and inflammation-related genes in lung squamous cell carcinoma.Semantic proximity Read ↗

A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers.Semantic proximity Read ↗

Caspase 9 promoter polymorphisms and risk of primary lung cancer.Semantic proximity Read ↗

Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.