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Article

A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility.

PloS one - 1 Jan 2012

Xu Wei, Jiang Shengqiang, Xu Yuanyuan, Chen Bo, Li Yan, Zong Feng, Zhao Weihong, Wu Jianqing

Abstract excerpt

BACKGROUND: Caspases are important regulators and executioners in apoptosis pathway and have been defined as either tumor suppressors or oncogenes. Polymorphisms in promoter and exon of caspase 9 were shown to confer genetic susceptibility to multiple cancers, but the results were inconsistent. To accomplish a more precise estimation of the relationship, a meta-analysis was performed. METHODOLOGY/PRINCIPAL...

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Identifiers

PMID: 22616010
DOI: 10.1371/journal.pone.0037443
PMCID: PMC3355128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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