Article
Polymorphisms in the caspase-8 gene and the risk of lung cancer.
Cancer genetics and cytogenetics - 1 Sept 2006
Son Ji-Woong, Kang Hyo-Kyung, Chae Myung Hwa, Choi Jin Eun, Park Jung Min, Lee Won Kee, Kim Chang Ho, Kim Dong Sun, Kam Sin, Kang Young Mo, Park Jae Yong
Abstract excerpt
Caspase-8 (CASP-8) is an initiator CASP in the cell death receptor-mediated apoptotic pathway, and plays an important role in the development of cancer. Polymorphisms and their haplotypes in the CASP-8 gene can result in alterations in CASP-8 expression and/or activity, thereby modulating the sus...
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