Article
Insulin receptor gene polymorphisms in type 2 (non-insulin-dependent) diabetes mellitus.
Diabetologia - 1 Apr 1991
Oelbaum R S, Bouloux P M, Li S R, Baroni M G, Stocks J, Galton D J
Abstract excerpt
The insulin receptor has been proposed as a candidate gene for the inherited defect in Type 2 (non-insulin-dependent) diabetes mellitus and we therefore studied three restriction fragment length polymorphic sites, two revealed with the enzyme Sst1 and one by Rsa1, using two insulin receptor cDNA probes in 131 Caucasian Type 2 diabetic patients and 94 control subjects. The frequency of the six alleles studied did...
Topics
- Aged
- Alleles
- DNA
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Exons
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
