Article
Allelic variants at insulin-receptor and insulin gene loci and susceptibility to NIDDM in Welsh population.
Diabetes - 1 Dec 1990
Morgan R, Bishop A, Owens D R, Luzio S D, Peters J R, Rees A
Abstract excerpt
A cohort of 132 well-documented White Welsh non-insulin-dependent diabetic (NIDDM) subjects were genotyped for 5 restriction-fragment-length polymorphisms (RFLPs) at the insulin-receptor gene (IRG) locus and a polymorphic locus 5' to the insulin gene. There was no significant difference in RFLP frequencies between the NIDDM subjects and a group of 87 matched White control subjects. Paired haplotype analysis of...
Topics
- Adult
- Alleles
- Chromosome Mapping
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Female
- Genetic Variation
- Haplotypes
- Humans
- Insulin
- Male
- Middle Aged
