Article
Bgl II-restriction fragment length polymorphism of the insulin receptor gene in patients with type-II diabetes mellitus.
Biomedica biochimica acta - 1 Jan 1990
Menzel S, Neumer C, Zorad S, Klimes I, Langerova H, Zühlke H
Abstract excerpt
As an approach to estimate the involvement of the insulin receptor gene in the etiopathogenesis of type-II diabetes mellitus we determined the distribution of the alleles of a restriction fragment length polymorphism of this gene (Bgl II-RFLP) in a group of type-II diabetics. The patients had been characterized by insulin and C-peptide values during OGTT and insulin receptor binding indices. The difference in...
Topics
- Alleles
- Bacterial Proteins
- DNA Probes
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Genotype
- Humans
- Polymorphism, Restriction Fragment Length
- Receptor, Insulin
