Article
Restriction site polymorphisms at the human HepG2 glucose transporter gene locus in Caucasian and west Indian subjects with non-insulin-dependent diabetes mellitus.
Human heredity - 1 Jan 1990
Li S R, Oelbaum R S, Bouloux P M, Stocks J, Baroni M G, Galton D J
Abstract excerpt
Digestion of human genomic DNA with the restriction enzyme StuI revealed a 2-allele polymorphism with a human HepG2 glucose transporter probe. Bands of 3.2 kilobases (kb; S1 allele) and 2.6 kb (S2 allele) were observed. The genotype frequencies were investigated in 2 non-insulin-dependent diabetic populations. The genotype frequencies of S1S1, S1S2 and S2S2 were 6, 42 and 52% among Caucasian diabetic subjects (n...
Topics
- Alleles
- Black People
- Diabetes Mellitus, Type 2
- Female
- Humans
- London
- Male
- Monosaccharide Transport Proteins
- Polymorphism, Restriction Fragment Length
- West Indies
- White People