Article
Serotonin-transporter-linked promoter region polymorphism and serotonin transporter binding in drug-naïve patients with major depression.
Psychiatry and clinical neurosciences - 1 Aug 2010
Joensuu Mikko, Lehto Soili Marianne, Tolmunen Tommi, Saarinen Pirjo Irmeli, Valkonen-Korhonen Minna, Vanninen Ritva, Ahola Pasi, Tiihonen Jari, Kuikka Jyrki, Pesonen Ullamari, Lehtonen Johannes
Abstract excerpt
AIMS: Both the serotonin transporter and its genetic regulation by the serotonin-transporter-linked polymorphic region have a role in the pathophysiology of depression. Most of the previous studies have found no influence of serotonin-transporter-linked polymorphic region allelic variation on serotonin transporter binding in healthy controls or patients with major depression. Due to the inconsistency of the...
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