Article
5-HT1A gene promoter polymorphism and [18F]MPPF binding potential in healthy subjects: a PET study.
Behavioral and brain functions : BBF - 7 Jul 2010
Lothe Amélie, Boni Claudette, Costes Nicolas, Bouvard Sandrine, Gorwood Philip, Lavenne Franck, Alvarez Marion, Ryvlin Philippe
Abstract excerpt
BACKGROUND: Previous Positron Emission Tomography (PET) studies of 5-HT1A receptors have shown an influence of several genetic factors, including the triallelic serotonin transporter gene-linked polymorphic region on the binding potential (BPND) of these receptors. The aim of our study was to investigate the relationship between a 5-HT1A promoter polymorphism and the binding potential of another selective 5-HT1A...
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