Article
Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression.
Psychiatry research - 30 Jun 2013
Ho Pei-Shen, Ho Kellen Kai-Jen, Huang Wen-Sheng, Yen Che-Hung, Shih Mei-Chen, Shen Lie-Hang, Ma Kuo-Hsing, Huang San-Yuan
Abstract excerpt
The serotonin transporter (SERT) is hypothesized to be an important component of the pathophysiology of major depression (MD). The aim of this study was to use [(123)I]ADAM single-photon emission computed tomography (SPECT) to explore whether SERT availability in four regions of the brain (striatum, thalamus, midbrain and pons) is different in patients with MD and healthy individuals. The effects of three genetic...
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