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Article

Role of Platelet-Derived Growth Factors in the Testis

1 Dec 2010

Abstract excerpt

Normal development and function of the testis are controlled by endocrine and paracrine signaling pathways. Platelet-derived growth factors (PDGFs) are growth factors that mediate epithelial-mesenchymal interactions in various tissues during normal and abnormal processes such as embryo development, wound healing, tissue fibrosis, vascular disorders, and cancer. PDGFs and their receptors (PDGFRs) have emerged as...

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PMID: 20650860
DOI: 10.1210/er.2010-0004

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