Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.

Genes & development - 15 Mar 2003

Brennan Jennifer, Tilmann Christopher, Capel Blanche

Abstract excerpt

During testis development, the rapid morphological changes initiated by Sry require the coordinate integration of many signaling pathways. Based on the established role of the platelet-derived growth factor (PDGF) family of ligands and receptors in migration, proliferation, and differentiation of cells in various organ systems, we have investigated the role of PDGF in testis organogenesis. Analysis of expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bromodeoxyuridine
Share to In Situ Hybridization
Share to Leydig Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Sex Determination Processes

Share to Testis

Share to X Chromosome

Share to Y Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 12651897
DOI: 10.1101/gad.1052503
PMCID: PMC196020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.PMID 12651897Read ↗

Role of Platelet-Derived Growth Factors in the TestisSemantic proximity Read ↗

Expression of Platelet-Derived Growth Factor-A (PDGF-A), PDGF-B, and PDGF Receptor-α and -β during Human Testicular Development and DiseaseSemantic proximity Read ↗

Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action.Semantic proximity Read ↗

Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.Semantic proximity Read ↗

Role of platelet-derived growth factors in physiology and medicine.Semantic proximity Read ↗

Platelet-Derived Growth Factor Receptor β-Subtype Regulates Proliferation and Migration of GonocytesSemantic proximity Read ↗

Yolk-sac–derived macrophages regulate fetal testis vascularization and morphogenesisSemantic proximity Read ↗

Roles of PDGF/PDGFR signaling in various organsSemantic proximity Read ↗

Identification and distribution of a novel platelet-derived growth factor receptor beta variant: effect of retinoic acid and involvement in cell differentiation.Semantic proximity Read ↗

Male-specific cell migration into the developing gonad is a conserved process involving PDGF signallingSemantic proximity Read ↗

Regulation of PDGF-BB Signaling in Placental Pericytes by Soluble PDGFRβ Isoforms: Implications for Fetoplacental Vascular DevelopmentSemantic proximity Read ↗

Platelet-Derived Growth Factor Receptor Alpha as a Marker of Mesenchymal Stem Cells in Development and Stem Cell BiologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.