Functional polymorphism in the neuropeptide Y gene promoter (rs16147) is associated with serum leptin levels and waist-hip ratio in women.

doi:10.1159/000346799

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Functional polymorphism in the neuropeptide Y gene promoter (rs16147) is associated with serum leptin levels and waist-hip ratio in women.

Annals of nutrition & metabolism - 1 Jan 2013

Mutschler Jochen, Abbruzzese Elvira, Wiedemann Klaus, von der Goltz Christoph, Dinter Christina, Mobascher Arian, Thiele Holger, Diaz-Lacava Amalia, Dahmen Norbert, Gallinat Jürgen, Majic Tomislav, Petrovsky Nadine, Thuerauf Norbert, Kornhuber Johannes, Gründer Gerhard, Rademacher Lena, Brinkmeyer Juergen, Wienker Thomas, Wagner Michael, Winterer Georg, Kiefer Falk

Abstract excerpt

OBJECTIVE: The neuropeptide-Y (NP-Y) gene is a strong candidate gene in the pathophysiology of obesity-linked behavior, and several single-nucleotide polymorphisms of NP-Y have already been linked to body weight and appetite. However, the results from current studies remain inconclusive. The aim of the present study was to test whether a certain functional genetic variant (SNP rs16147) in the NP-Y promoter gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Leptin

Share to Neuropeptide Y

Share to Obesity

Share to Sex Factors

Share to Statistics, Nonparametric

Share to Waist-Hip Ratio

Share to White People

Source

Open in PubMed

Identifiers

PMID: 23652383
DOI: 10.1159/000346799

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphism in the neuropeptide Y gene promoter (rs16147) is associated with serum leptin levels and waist-hip ratio in women.PMID 23652383Read ↗

Association of Neuropeptide Y Gene rs16147 Polymorphism with Cardiovascular Risk Factors, Adipokines, and Metabolic Syndrome in Patients with Obesity.Semantic proximity Read ↗

Polymorphisms in the neuropeptide Y gene and the risk of obesity: findings from two prospective cohorts.Semantic proximity Read ↗

Polymorphism of neuropeptide Y gene rs16147 modifies the response to a hypocaloric diet on cardiovascular risk biomarkers and adipokines.Semantic proximity Read ↗

Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial.Semantic proximity Read ↗

Comprehensive evaluation of the neuropeptide-Y gene variants in the risk of obesity: a case-control study and meta-analysis.Semantic proximity Read ↗

Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.Semantic proximity Read ↗

Influence of variants in the NPY gene on obesity and metabolic syndrome features in Spanish children.Semantic proximity Read ↗

Genetic variation in the neuropeptide Y gene promoter is associated with increased risk of tobacco smoking.Semantic proximity Read ↗

Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study.Semantic proximity Read ↗

Neuropeptide Y promoter polymorphism modifies effects of a weight-loss diet on 2-year changes of blood pressure: the preventing overweight using novel dietary strategies trial.Semantic proximity Read ↗

Association of neuropeptide Y gene rs16147 polymorphism with metabolic syndrome in patients with documented coronary artery disease.Semantic proximity Read ↗

[Effect of a Mediterranean-pattern diet on the metabolic response secondary to weight loss; role of the single nucleotide polymorphism (rs16147) of neuropeptide Y].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.