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Article

Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity.

Translational psychiatry - 17 Apr 2012

Weickert C S, Tiwari Y, Schofield P R, Mowry B J, Fullerton J M

Abstract excerpt

Excitement and controversy have followed neuregulin (NRG1) since its discovery as a putative schizophrenia susceptibility gene; however, the mechanism of action of the associated risk haplotype (HapICE) has not been identified, and specific genetic variations, which may increase risk to schizophrenia have remained elusive. Using a postmortem brain cohort from 37 schizophrenia cases and 37 controls, we resequenced...

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Source

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Identifiers

PMID: 22832904
DOI: 10.1038/tp.2012.25
PMCID: PMC3337073

Genes

NRG1
BDNF
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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