Article
A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.
Genesis (New York, N.Y. : 2000) - 1 Sept 2010
Vincent David F, Kaniewski Bastien, Powers Shannon E, Havenar-Daughton Colin, Marie Julien C, Wotton David, Bartholin Laurent
Abstract excerpt
We have previously generated a transgenic mouse strain (LSL-TβRI(CA)) containing a Cre-inducible constitutively active TGFβ type I receptor (Bartholin et al., 2008, Genesis 46: 724-731). Transgene expression depends on the excision of a floxed-transcriptional STOP (LSL, Lox-STOP-Lox) located upst...
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