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R/L, a double reporter mouse line that expresses luciferase gene upon Cre-mediated excision, followed by inactivation of mRFP expression.

Genome - 1 Oct 2016

Jia Junshuang, Lin Xiaolin, Lin Xia, Lin Taoyan, Chen Bangzhu, Hao Weichao, Cheng Yushuang, Liu Yu, Dian Meijuan, Yao Kaitai, Xiao Dong, Gu Weiwang

Abstract excerpt

The Cre/loxP system has become an important tool for the conditional gene knockout and conditional gene expression in genetically engineered mice. The applications of this system depend on transgenic reporter mouse lines that provide Cre recombinase activity with a defined cell type-, tissue-, or developmental stage-specificity. To develop a sensitive assay for monitoring Cre-mediated DNA excisions in mice, we...

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PMID: 27643679
DOI: 10.1139/gen-2016-0090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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