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Article

Generation of mice with a conditional allele for transforming growth factor beta 1 gene.

Genesis (New York, N.Y. : 2000) - 1 Jun 2009

Azhar Mohamad, Yin Moying, Bommireddy Ramireddy, Duffy John J, Yang Junqi, Pawlowski Sharon A, Boivin Gregory P, Engle Sandra J, Sanford L P, Grisham Christina, Singh Ram R, Babcock George F, Doetschman Thomas

Abstract excerpt

Transforming growth factor beta1 (TGFbeta1) is a multifunctional growth factor involved in wound healing, tissue fibrosis, and in the pathogenesis of many syndromic diseases (e.g., Marfan syndrome, Camurati-Engelmann disease) and muscular, neurological, ophthalmic, cardiovascular and immunological disorders, and cancer. Since the generation of Tgfb1 knockout mice, there has been extraordinary progress in...

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Identifiers

PMID: 19415629
DOI: 10.1002/dvg.20516
PMCID: PMC2766615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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