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Article

Distribution of some activating KRAS and BRAF mutations in Slovene patients with colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Dec 2011

Ličar Alenka, Cerkovnik Petra, Novaković Srdjan

Abstract excerpt

Numerous clinical studies have shown that anti-EGFR therapies are effective only in a subset of patients with colorectal cancer. Even though mutations in the KRAS gene have been confirmed as negative predictors of the response to EGFR-targeted therapies, not all KRAS wild-type (wt-KRAS) patients will respond to treatment. Recent studies have demonstrated that additionally wild-type BRAF (wt-BRAF) genotype is...

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Identifiers

PMID: 20645028
DOI: 10.1007/s12032-010-9631-z

Genes

KRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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