Article
KRAS and BRAF mutations in Serbian patients with colorectal cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Jakovljevic K, Malisic E, Cavic M, Krivokuca A, Dobricic J, Jankovic R
Abstract excerpt
PURPOSE: Mutations of KRAS and BRAF genes represent molecular biomarkers of response to targeted therapy in patients with metastatic colorectal cancer (mCRC). Since these mutations have been shown to exert different biological effects and impacts on patients' outcome, there is a need to determine...
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