Article
Mutation pattern of KRAS and BRAF oncogenes in colorectal cancer patients.
Neoplasma - 1 Jan 2012
Rako I, Jakic-Razumovic J, Katalinic D, Sertic J, Plestina S
Abstract excerpt
The aim of this study was to identify KRAS and BRAF gene mutations in colorectal cancer patients and to assess whether they are linked with clinicopathological features. The results of KRAS and BRAF mutation analysis could be used in the selection of patients for anti-EGFR therapy. All specimens were obtained during routine surgery of patients with colorectal carcinoma. The diagnoses were established by standard...
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