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Article

KRAS mutations in Slovene patients with colorectal cancer: frequency, distribution and correlation with the response to treatment.

International journal of oncology - 1 May 2010

Licar Alenka, Cerkovnik Petra, Ocvirk Janja, Novakovic Srdjan

Abstract excerpt

KRAS mutations are proved as a predictor of response to EGFR-targeted therapies for patients with metastatic colorectal cancer. For identifying the wild-type KRAS (wt-KRAS) responder subset of patients who will benefit from novel agents our laboratory has introduced the TheraSreen K-RAS Mutation Kit(R) an allele-specific RT-PCR based assay. Our aim is to describe the validation procedure of this method in our...

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Source

Identifiers

PMID: 20372787
DOI: 10.3892/ijo_00000596

Genes

KRAS
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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