Article
Association study of catechol-O-methyltransferase gene polymorphisms with schizophrenia and psychopathological symptoms in Han Chinese.
Genes, brain, and behavior - 1 Apr 2011
Chen C-Y, Lu R-B, Yeh Y-W, Shih M-C, Huang S-Y
Abstract excerpt
Although dysfunction of catechol-O-methyltransferase (COMT)-mediated dopamine transmission is implicated in the etiology of schizophrenia, the human COMT gene has not been associated consistently with schizophrenia. The purpose of this study was to investigate whether the COMT gene is associated with the development of schizophrenia and whether the polymorphisms of this gene influence the psychopathological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.