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Article

Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort.

The Journal of antimicrobial chemotherapy - 1 Sept 2010

Carr Daniel F, la Porte Charles J L, Pirmohamed Munir, Owen Andrew, Cortes Claudia P

Abstract excerpt

OBJECTIVES: Efavirenz is extensively metabolized by CYP2B6, and associations between CYP2B6 polymorphisms and plasma efavirenz exposure have been reported. The objective of this study was to investigate CYP2B6 haplotype structure and functional consequences in a Latin American population. PATIENTS AND METHODS: Two hundred and nineteen patients were recruited at Fundación Arriarán, Chile, between September and...

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Identifiers

PMID: 20639527
DOI: 10.1093/jac/dkq260
PMCID: PMC2920179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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