Article
Effect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV Infection.
PloS one - 1 Jan 2015
Meng Xianmin, Yin Kang, Wang Jiangrong, Dong Ping, Liu Li, Shen Yinzhong, Shen Li, Ma Qing, Lu Hongzhou, Cai Weimin
Abstract excerpt
OBJECTIVES: The main aim of this study was to investigate the effect of CYP2B6 gene polymorphisms on efavirenz (EFV) plasma concentrations in Han Chinese patients with human immunodeficiency virus (HIV) infection. METHODS: In total, 322 patients were recruited for study. EFV plasma concentrations at steady-state were determined using high-performance liquid chromatography. Genotyping for seven single nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
