Article
Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability.
Clinical journal of the American Society of Nephrology : CJASN - 1 Nov 2010
Hastings M Colleen, Moldoveanu Zina, Julian Bruce A, Novak Jan, Sanders John T, McGlothan Kim R, Gharavi Ali G, Wyatt Robert J
Abstract excerpt
BACKGROUND AND OBJECTIVES: Serum levels of galactose-deficient IgA1 (Gd-IgA1) are elevated and heritable in Caucasian and Asian patients with IgA nephropathy (IgAN), but have not been characterized in African Americans (AA). Our objective was to determine whether serum Gd-IgA1 levels are increased in AA patients with IgAN and whether this is a heritable trait in this group. DESIGN, SETTING, PARTICIPANTS, &...
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